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CEBPA 抗体 (AA 1-124)

Name: CEBPA 抗体 (AA 1-124)
Brand: antibodies-online
SKU: ABIN7147076
Availability: OutOfStock

This anti-CEBPA antibody is a 兔多克隆 antibody detecting CEBPA in WB, ELISA 和 IHC. Suitable for 人.

Western Blot Positive WB detected in: A549 whole cell lysate, HepG2 whole cell lysate, MCF-7 whole cell lysate All lanes: CEBPA antibody at 2 μg/mL Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 38, 36, 26, 42 kDa Observed band size: 38 kDa (CEBPA 抗体 (AA 1-124))

Immunohistochemistry of paraffin-embedded human pancreatic tissue using ABIN7147076 at dilution of 1:100 (CEBPA 抗体 (AA 1-124))

IHC

2 images

产品编号 ABIN7147076

发货至: 中国

Quick Overview for CEBPA 抗体 (AA 1-124) (ABIN7147076)

抗原

See all CEBPA 抗体

CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

适用

人

宿主

兔

克隆类型

多克隆

标记

This CEBPA antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Discover our top product CEBPA Primary Antibody

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AA 1-124

交叉反应

人

纯化方法

>95%, Protein G purified

免疫原

Recombinant Human CCAAT/enhancer-binding protein alpha protein (1-124AA)

亚型

IgG
anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibody
CEBPA 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5B7 unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibody
CEBPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (pSer21) antibody
CEBPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (AA 1-205) antibody
CEBPA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (pThr226) antibody
CEBPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (AA 288-337) antibody
CEBPA 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, Pig, 犬, 兔, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (N-Term) antibody
CEBPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (N-Term) antibody
KO Validated CEBPA 适用: 人 WB, IHC (p), IP, ChIP 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) (Middle Region) antibody
CEBPA 适用: 人, 小鼠, 大鼠, Cow, 斑马鱼, 豚鼠, 犬, 兔, 马, 绵羊 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) antibody
CEBPA 适用: 人 WB, FACS, EIA 宿主: 小鼠 Monoclonal 4-00E-010 unconjugated

应用备注

Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

限制

仅限研究用
状态

Liquid

缓冲液

Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C,-80 °C

储存方法

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
抗原

CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

别名

CEBPA

背景

Background: Transcription factor that coordinates proliferation arrest and the differentiation of myeloid progenitors, adipocytes, hepatocytes, and cells of the lung and the placenta. Binds directly to the consensus DNA sequence 5\\\'-T[TG]NNGNAA[TG]-3\\\' acting as an activator on distinct target genes (PubMed:11242107). During early embryogenesis, plays essential and redundant functions with CEBPB. Essential for the transition from common myeloid progenitors (CMP) to granulocyte/monocyte progenitors (GMP). Critical for the proper development of the liver and the lung (By similarity). Necessary for terminal adipocyte differentiation, is required for postnatal maintenance of systemic energy homeostasis and lipid storage (By similarity). To regulate these different processes at the proper moment and tissue, interplays with other transcription factors and modulators. Downregulates the expression of genes that maintain cells in an undifferentiated and proliferative state through E2F1 repression, which is critical for its ability to induce adipocyte and granulocyte terminal differentiation. Reciprocally E2F1 blocks adipocyte differentiation by binding to specific promoters and repressing CEBPA binding to its target gene promoters. Proliferation arrest also depends on a functional binding to SWI/SNF complex (PubMed:14660596). In liver, regulates gluconeogenesis and lipogenesis through different mechanisms. To regulate gluconeogenesis, functionally cooperates with FOXO1 binding to IRE-controlled promoters and regulating the expression of target genes such as PCK1 or G6PC. To modulate lipogenesis, interacts and transcriptionally synergizes with SREBF1 in promoter activation of specific lipogenic target genes such as ACAS2. In adipose tissue, seems to act as FOXO1 coactivator accessing to ADIPOQ promoter through FOXO1 binding sites (By similarity).
Aliases: Apoptotic cysteine protease antibody, Apoptotic protease Mch 5 antibody, C/EBP alpha antibody, C/ebpalpha antibody, CAP4 antibody, Caspase 8 precursor antibody, CBF-A antibody, CCAAT Enhancer Binding Protein alpha antibody, CCAAT/enhancer binding protein (C/EBP), alpha antibody, CCAAT/enhancer-binding protein alpha antibody, CEBP antibody, CEBP A antibody, CEBP alpha antibody, Cebpa antibody, CEBPA_HUMAN antibody, FADD homologous ICE/CED 3 like protease antibody, FADD like ICE antibody, FLICE antibody, ICE like apoptotic protease 5 antibody, ICE8 antibody, MACH antibody, MCH5 antibody, MORT1 associated CED 3 homolog antibody

UniProt

P49715

途径

Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation