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CATSPER4 抗体 (AA 306-472) (Biotin)

CATSPER4 适用: 人 ELISA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN7147036
发货至: 中国
  • 抗原 See all CATSPER4 抗体
    CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
    抗原表位
    • 15
    • 4
    • 1
    • 1
    AA 306-472
    适用
    • 20
    • 1
    • 1
    宿主
    • 21
    克隆类型
    • 21
    多克隆
    标记
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CATSPER4 antibody is conjugated to Biotin
    应用范围
    • 16
    • 13
    • 13
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Cation channel sperm-associated protein 4 protein (306-472AA)
    亚型
    IgG
    Top Product
    Discover our top product CATSPER4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
    别名
    CATSPER4 (CATSPER4 产品)
    别名
    RGD1565213 antibody, 4933412L05 antibody, cation channel, sperm associated 4 antibody, cation channel sperm associated 4 antibody, Catsper4 antibody, CATSPER4 antibody
    背景

    Background: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials, it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH .

    Aliases: CATSPER4Cation channel sperm-associated protein 4 antibody, CatSper4 antibody

    UniProt
    Q7RTX7
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