CATSPER4 抗体 (AA 306-472)
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北京 101111
Quick Overview for CATSPER4 抗体 (AA 306-472) (ABIN7147035)
抗原
See all CATSPER4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 306-472
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原理
- CATSPER4 Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Cation channel sperm-associated protein 4 protein (306-472AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
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别名
- CATSPER4
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背景
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Background: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials, it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH .
Aliases: CATSPER4Cation channel sperm-associated protein 4 antibody, CatSper4 antibody
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UniProt
- Q7RTX7
抗原
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