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CSNK2A2 抗体 (AA 8-350) (HRP)

This anti-CSNK2A2 antibody (ABIN7146891) is a Rabbit Polyclonal antibody detecting CSNK2A2 in ELISA. Suitable for Human.
产品编号 ABIN7146891
发货至: 中国

Quick Overview for CSNK2A2 抗体 (AA 8-350) (HRP) (ABIN7146891)

抗原

See all CSNK2A2 抗体
CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))

适用

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宿主

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克隆类型

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多克隆

标记

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This CSNK2A2 antibody is conjugated to HRP

应用范围

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ELISA
  • 抗原表位

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    AA 8-350

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Casein kinase II subunit alpha' protein (8-350AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CSNK2A2 (Casein Kinase 2, alpha Prime Polypeptide (CSNK2A2))

    别名

    CSNK2A2

    背景

    Background: Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly checkpoint (SAC) that maintains cyclin-B-CDK1 activity and G2 arrest in response to spindle damage. Also required for p53/TP53-mediated apoptosis, phosphorylating 'Ser-392' of p53/TP53 following UV irradiation. Can also negatively regulate apoptosis. Phosphorylates the caspases CASP9 and CASP2 and the apoptotic regulator NOL3. Phosphorylation protects CASP9 from cleavage and activation by CASP8, and inhibits the dimerization of CASP2 and activation of CASP8. Regulates transcription by direct phosphorylation of RNA polymerases I, II, III and IV. Also phosphorylates and regulates numerous transcription factors including NF-kappa-B, STAT1, CREB1, IRF1, IRF2, ATF1, SRF, MAX, JUN, FOS, MYC and MYB. Phosphorylates Hsp90 and its co-chaperones FKBP4 and CDC37, which is essential for chaperone function. Regulates Wnt signaling by phosphorylating CTNNB1 and the transcription factor LEF1. Acts as an ectokinase that phosphorylates several extracellular proteins. During viral infection, phosphorylates various proteins involved in the viral life cycles of EBV, HSV, HBV, HCV, HIV, CMV and HPV.

    Aliases: Casein kinase 2 alpha prime polypeptide antibody, Casein kinase II alpha' chain antibody, Casein kinase II subunit alpha' antibody, CK II alpha' antibody, CK II antibody, CK2A2 antibody, CKII antibody, CSK22_HUMAN antibody, CSNK2A1 antibody, CSNK2A2 antibody, FLJ43934 antibody

    UniProt

    P19784

    途径

    SARS-CoV-2 Protein Interactome
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