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COMP 抗体 (AA 20-160)

This anti-COMP antibody is a 兔 多克隆 antibody detecting COMP in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7146850
发货至: 中国

Quick Overview for COMP 抗体 (AA 20-160) (ABIN7146850)

抗原

See all COMP 抗体
COMP (Cartilage Oligomeric Matrix Protein (COMP))

适用

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宿主

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克隆类型

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多克隆

标记

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This COMP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    AA 20-160

    交叉反应

    人, 小鼠

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Cartilage oligomeric matrix protein (20-160AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:2000,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    COMP (Cartilage Oligomeric Matrix Protein (COMP))

    别名

    COMP

    背景

    Background: May play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Could play a role in the pathogenesis of osteoarthritis. Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7.

    Aliases: cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple) antibody, Cartilage oligomeric matrix protein antibody, Cartilage oligomeric matrix protein precursor antibody, COMP antibody, COMP_HUMAN antibody, EDM 1 antibody, EDM1 antibody, EPD 1 antibody, EPD1 antibody, Epiphyseal dysplasia 1 antibody, Epiphyseal dysplasia 1 multiple antibody, Epiphyseal dysplasia multiple 1 antibody, MED antibody, MGC13181 antibody, MGC149768 antibody, PSACH antibody, pseudoachondroplasia (epiphyseal dysplasia 1, multiple) antibody, Pseudoachondroplasia antibody, THBS 5 antibody, THBS5 antibody, Thrombospondin 5 antibody, Thrombospondin-5 antibody, Thrombospondin5 antibody, TSP5 antibody

    UniProt

    P49747
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