CBR1 抗体 (AA 176-268)
Quick Overview for CBR1 抗体 (AA 176-268) (ABIN7146741)
抗原
See all CBR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 176-268
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Carbonyl reductase [NADPH] 1 protein (176-268AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CBR1 (Carbonyl Reductase 1 (CBR1))
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别名
- CBR1
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背景
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Background: NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
Aliases: 15 hydroxyprostaglandin dehydrogenase [NADP+] antibody, 15-hydroxyprostaglandin dehydrogenase [NADP+] antibody, Carbonyl reductase [NADPH] 1 antibody, Carbonyl Reductase 1 antibody, CBR 1 antibody, CBR1 antibody, CBR1_HUMAN antibody, CRN antibody, NADPH dependent carbonyl reductase 1 antibody, NADPH-dependent carbonyl reductase 1 antibody, Prostaglandin 9 ketoreductase antibody, Prostaglandin 9-ketoreductase antibody, Prostaglandin E(2) 9 reductase antibody, Prostaglandin-E(2) 9-reductase antibody, SDR21C1 antibody
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UniProt
- P16152
抗原
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