CAMK1 抗体 (AA 166-265)
Quick Overview for CAMK1 抗体 (AA 166-265) (ABIN7146428)
抗原
See all CAMK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 166-265
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Calcium/calmodulin-dependent protein kinase type 1 protein (166-265AA)
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亚型
- IgG
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anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (AA 1-93) antibody
CAMK1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (AA 271-370) antibodyCAMK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B6 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (AA 341-370), (C-Term) antibodyCAMK1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC (p) 宿主: 兔 Polyclonal RB1255 unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (AA 143-192), (pThr177) antibodyCAMK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (pSer177) antibodyCAMK1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) antibodyCAMK1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (C-Term) antibodyCAMK1 适用: 人, 小鼠, 大鼠, 灵长类 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) antibodyCAMK1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (C-Term) antibodyCAMK1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium/calmodulin-Dependent Protein Kinase I (CAMK1) (Internal Region) antibodyCAMK1 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CAMK1 (Calcium/calmodulin-Dependent Protein Kinase I (CAMK1))
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别名
- CAMK1
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背景
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Background: Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, regulates transcription activators activity, cell cycle, hormone production, cell differentiation, actin filament organization and neurite outgrowth. Recognizes the substrate consensus sequence [MVLIF]-x-R-x(2)-[ST]-x(3)-[MVLIF]. Regulates axonal extension and growth cone motility in hippocampal and cerebellar nerve cells. Upon NMDA receptor-mediated Ca(2+) elevation, promotes dendritic growth in hippocampal neurons and is essential in synapses for full long-term potentiation (LTP) and ERK2-dependent translational activation. Downstream of NMDA receptors, promotes the formation of spines and synapses in hippocampal neurons by phosphorylating ARHGEF7/BETAPIX on \\\'Ser-694\\\', which results in the enhancement of ARHGEF7 activity and activation of RAC1. Promotes neuronal differentiation and neurite outgrowth by activation and phosphorylation of MARK2 on \\\'Ser-91\\\', \\\'Ser-92\\\', \\\'Ser-93\\\' and \\\'Ser-294\\\'. Promotes nuclear export of HDAC5 and binding to 14-3-3 by phosphorylation of \\\'Ser-259\\\' and \\\'Ser-498\\\' in the regulation of muscle cell differentiation. Regulates NUMB-mediated endocytosis by phosphorylation of NUMB on \\\'Ser-276\\\' and \\\'Ser-295\\\'. Involved in the regulation of basal and estrogen-stimulated migration of medulloblastoma cells through ARHGEF7/BETAPIX phosphorylation (By similarity). Is required for proper activation of cyclin-D1/CDK4 complex during G1 progression in diploid fibroblasts. Plays a role in K(+) and ANG2-mediated regulation of the aldosterone synthase (CYP11B2) to produce aldosterone in the adrenal cortex. Phosphorylates EIF4G3/eIF4GII. In vitro phosphorylates CREB1, ATF1, CFTR, MYL9 and SYN1/synapsin I.
Aliases: Calcium / calmodulin dependent protein kinase 1 antibody, Calcium / calmodulin dependent protein kinase I antibody, Calcium / calmodulin dependent protein kinase type 1 antibody, Calcium/calmodulin dependent protein kinase 1 antibody, Calcium/calmodulin dependent protein kinase I antibody, Calcium/calmodulin dependent protein kinase type 1 antibody, Calcium/calmodulin-dependent protein kinase type 1 antibody, CaM K1 antibody, CaM KI antibody, CaM kinase 1 alpha antibody, CAM kinase 1 antibody, CaM kinase I alpha antibody, CaM kinase I antibody, CaM-KI antibody, CaMK 1 antibody, CAMK I antibody, CaMK1 alpha antibody, CAMK1 antibody, CAMK1 PEN antibody, CaMKI alpha antibody, CaMKI-alpha antibody, KCC1A_HUMAN antibody, MGC120317 antibody, MGC120318 antibody
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UniProt
- Q14012
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途径
- Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Smooth Muscle Cell Migration
抗原
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