CAMKK2 抗体 (AA 5-148)
Quick Overview for CAMKK2 抗体 (AA 5-148) (ABIN7146424)
抗原
See all CAMKK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 5-148
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交叉反应
 - 人
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纯化方法
 - >95%, Protein G purified
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免疫原
 - Recombinant Human Calcium/calmodulin-dependent protein kinase kinase 2 protein (5-148AA)
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亚型
 - IgG
 
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应用备注
 - Recommended dilution: IHC:1:20-1:200,
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
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                        Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 
                                            
储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
 - -20 °C,-80 °C
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储存方法
 - Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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- CAMKK2 (Calcium/calmodulin-Dependent Protein Kinase Kinase 2, beta (CAMKK2))
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别名
 - CAMKK2
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背景
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Background: Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals (By similarity). Seems to be involved in hippocampal activation of CREB1 (By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
Aliases: Calcium/calmodulin dependent protein kinase beta antibody, Calcium/calmodulin dependent protein kinase kinase 2 antibody, Calcium/calmodulin dependent protein kinase kinase 2 beta antibody, Calcium/calmodulin dependent protein kinase kinase beta antibody, Calcium/calmodulin-dependent protein kinase kinase 2 antibody, Calcium/calmodulin-dependent protein kinase kinase beta antibody, CaM kinase kinase beta antibody, CaM KK beta antibody, CaM-kinase kinase 2 antibody, CaM-kinase kinase beta antibody, CaM-KK 2 antibody, CaM-KK beta antibody, CaMKK 2 antibody, CAMKK antibody, CaMKK beta antibody, CAMKK beta protein antibody, Camkk2 antibody, CAMKKB antibody, KKCC2_HUMAN antibody
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UniProt
 - Q96RR4
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途径
 - AMPK Signaling
 
抗原
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