SS18L1 抗体 (AA 47-396)
Quick Overview for SS18L1 抗体 (AA 47-396) (ABIN7146400)
抗原
See all SS18L1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 47-396
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原理
- SS18L1 Antibody
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交叉反应
- 小鼠
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human Calcium-responsive transactivator protein (47-396AA)
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亚型
- IgG
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anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (AA 251-300) antibody
SS18L1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 小鸡, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1) (Middle Region) antibodySS18L1 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SS18L1 (Synovial Sarcoma Translocation Gene On Chromosome 18-Like 1 (SS18L1))
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别名
- SS18L1
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背景
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Background: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity).
Aliases: Calcium-responsive transactivator antibody, CREST antibody, CREST_HUMAN antibody, KIAA0693 antibody, LP2261 antibody, MGC26711 antibody, MGC78386 antibody, sarcoma translocation gene on chromosome18like1 antibody, SS18 antibody, SS18-like protein 1 antibody, SS18L1 antibody, SS18L1 nBAF chromatin remodeling complex antibody, SSXT antibody, synovial sarcoma translocation antibody, synovial sarcoma translocation gene on chromosome 18-like 1 antibody, SYT homolog 1 antibody
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UniProt
- O75177
抗原
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