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CALCOCO1 抗体 (AA 462-691)

This anti-CALCOCO1 antibody is a 兔 多克隆 antibody detecting CALCOCO1 in WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN7146346
发货至: 中国

Quick Overview for CALCOCO1 抗体 (AA 462-691) (ABIN7146346)

抗原

See all CALCOCO1 抗体
CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))

适用

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宿主

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克隆类型

  • 19
多克隆

标记

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This CALCOCO1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 462-691

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Calcium-binding and coiled-coil domain-containing protein 1 protein (462-691AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))

    别名

    CALCOCO1

    背景

    Background: Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR). Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions (By similarity). In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells (PubMed:24245781).

    Aliases: CALCOCO1 antibody, KIAA1536 antibody, PP13275 antibody, UNQ2436/PRO4996Calcium-binding and coiled-coil domain-containing protein 1 antibody, Calphoglin antibody, Coiled-coil coactivator protein antibody, Sarcoma antigen NY-SAR-3 antibody

    UniProt

    Q9P1Z2

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Chromatin Binding
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