KCNMA1 抗体 (AA 1-86)
Our Local Distributor
北京 101111
Quick Overview for KCNMA1 抗体 (AA 1-86) (ABIN7146334)
抗原
See all KCNMA1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-86
-
原理
- KCNMA1 Antibody
-
纯化方法
- Protein G purified
-
纯度
- >95 %
-
免疫原
- Recombinant Human Calcium-activated potassium channel subunit alpha-1 protein (1-86AA)
-
亚型
- IgG
-
-
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (C-Term) antibody
KCNMA1 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 兔, 犬, 马, 豚鼠, 绵羊 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 124-467) antibodyKCNMA1 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 199-213), (Extracellular) antibodyKCNMA1 适用: 大鼠 IHC, WB, IF, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1131-1236) antibodyKCNMA1 适用: 小鼠, 大鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1080-1129) antibodyKCNMA1 适用: 人, 小鼠, 大鼠, Cow, 兔, 马, 豚鼠, 绵羊, 小鸡, 非洲爪蟾, 猴, Pig, Bat IHC, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (Internal Region) antibodyKCNMA1 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 兔, 犬, 小鸡, 非洲爪蟾, 猴, Pig, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1184-1200), (Intracellular) antibodyKO Validated KCNMA1 适用: 小鼠 IHC, WB, IP, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 1097-1196), (Intracellular) antibodyKCNMA1 适用: 小鼠 WB 宿主: 豚鼠 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (Internal Region) antibodyKCNMA1 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1) (AA 118-152) antibodyKCNMA1 适用: 人 WB 宿主: 兔 Polyclonal RB53642 unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- KCNMA1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))
-
别名
- KCNMA1
-
背景
-
Background: Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca(2+), caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX).
Aliases: subfamily M subunit alpha-1 antibody, BK channel antibody, BKCA alpha antibody, BKCA alpha subunit antibody, BKTM antibody, Calcium-activated potassium channel antibody, Calcium-activated potassium channel subunit alpha-1 antibody, Drosophila slowpoke like antibody, hSlo antibody, K(VCA)alpha antibody, KCa1.1 antibody, KCMA1_HUMAN antibody, KCNMA antibody, KCNMA1 antibody, Maxi K channel antibody, Maxi Potassium channel alpha antibody, MaxiK antibody, SAKCA antibody, SLO alpha antibody, SLO antibody, Slo homolog antibody, Slo-alpha antibody, Slo1 antibody, Slowpoke homolog antibody
-
UniProt
- Q12791
-
途径
- Regulation of Hormone Metabolic Process, Sensory Perception of Sound
抗原
-
