ZNF224 抗体 (AA 206-463)
Quick Overview for ZNF224 抗体 (AA 206-463) (ABIN7145868)
抗原
See all ZNF224 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 206-463
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human BUB3-interacting and GLEBS motif-containing protein ZNF207 protein (206-463AA)
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亚型
- IgG
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anti-Zinc Finger Protein 224 (ZNF224) (AA 477-607) antibody
ZNF224 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 224 (ZNF224) (AA 95-190) antibodyZNF224 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C12 unconjugated
anti-Zinc Finger Protein 224 (ZNF224) (AA 612-661) antibodyZNF224 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 224 (ZNF224) (AA 124-173) antibodyZNF224 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 224 (ZNF224) (AA 395-444) antibodyZNF224 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ZNF224 (Zinc Finger Protein 224 (ZNF224))
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别名
- ZNF27
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背景
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Background: Kinetochore- and microtubule-binding protein that plays a key role in spindle assembly (PubMed:24462186, PubMed:24462187, PubMed:26388440). ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks (PubMed:26388440). Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of BUB3 (PubMed:24462186, PubMed:24462187). Mechanisms by which BUB3 is protected are unclear: according to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3 (PubMed:24462186). According to another report, the stabilization is independent of the proteasome (PubMed:24462187).
Aliases: Zinc finger protein 207 antibody, ZN207_HUMAN antibody, ZNF 207 antibody, ZNF207 antibody
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UniProt
- O43670
抗原
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