KCTD6 抗体 (AA 1-237) (Biotin)
Quick Overview for KCTD6 抗体 (AA 1-237) (Biotin) (ABIN7145857)
抗原
See all KCTD6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-237
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human BTB/POZ domain-containing protein KCTD6 protein (1-237AA)
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亚型
- IgG
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anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 1-237) antibody
KCTD6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (N-Term) antibodyKCTD6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (N-Term) antibodyKCTD6 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 1-237) antibodyKCTD6 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 72-121) antibodyKCTD6 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (AA 21-70) antibodyKCTD6 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Channel Tetramerisation Domain Containing 6 (KCTD6) (N-Term) antibodyKCTD6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- KCTD6 (Potassium Channel Tetramerisation Domain Containing 6 (KCTD6))
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别名
- KCTD6
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背景
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Background: Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1, the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1, the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation (PubMed:22573887).
Aliases: BTB/POZ domain-containing protein KCTD6 antibody, KCASH3 antibody, kctd6 antibody, KCTD6_HUMAN antibody, MGC27385 antibody, potassium channel tetramerization domain containing 6 antibody
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UniProt
- Q8NC69
抗原
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