BRD8 抗体 (AA 641-859) (HRP)
Quick Overview for BRD8 抗体 (AA 641-859) (HRP) (ABIN7145823)
抗原
See all BRD8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 641-859
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Bromodomain-containing protein 8 protein (641-859AA)
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亚型
- IgG
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anti-Bromodomain Containing 8 (BRD8) (AA 797-951) antibody
BRD8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 8 (BRD8) (N-Term) antibodyBRD8 适用: 人 WB, ChIP-seq, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 8 (BRD8) (AA 331-430) antibodyBRD8 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 8 (BRD8) (AA 641-859) antibodyBRD8 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 8 (BRD8) (AA 539-588) antibodyBRD8 适用: 人, 兔 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 8 (BRD8) (AA 33-128) antibodyBRD8 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 3G8 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BRD8 (Bromodomain Containing 8 (BRD8))
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别名
- BRD8
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背景
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Background: May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Isoform 2 stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. At least isoform 1 and isoform 2 are components of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
Aliases: BRD8 antibody, SMAP antibody, SMAP2 antibody, Bromodomain-containing protein 8 antibody, Skeletal muscle abundant protein antibody, Skeletal muscle abundant protein 2 antibody, Thyroid hormone receptor coactivating protein of 120 kDa antibody, TrCP120 antibody, p120 antibody
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UniProt
- Q9H0E9
抗原
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