BRD7 抗体 (AA 601-651) (Biotin)
Quick Overview for BRD7 抗体 (AA 601-651) (Biotin) (ABIN7145817)
抗原
See all BRD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 601-651
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Bromodomain-containing protein 7 protein (601-651AA)
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亚型
- IgG
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anti-Bromodomain Containing 7 (BRD7) (Internal Region) antibody
BRD7 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 1-95) antibodyBRD7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (C-Term) antibodyBRD7 适用: 人, 大鼠, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 601-651) antibodyBRD7 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 387-418) antibodyBRD7 适用: 小鼠 WB 宿主: 兔 Polyclonal RB43270 unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 514-567) antibodyBRD7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 1-651) antibodyBRD7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (C-Term) antibodyBRD7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BRD7 (Bromodomain Containing 7 (BRD7))
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别名
- BRD7
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背景
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Background: Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at \\\'Tyr-216\\\'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at \\\'Lys-9\\\' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at \\\'Lys-382\\\', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.
Aliases: 75 kDa bromodomain protein antibody, BP75 antibody, BRD 7 antibody, BRD7 antibody, BRD7_HUMAN antibody, Bromodomain containing 7 antibody, bromodomain containing protein 7 antibody, Bromodomain-containing protein 7 antibody, CELTIX 1 antibody, CELTIX1 antibody, NAG4 antibody, Protein CELTIX-1 antibody
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UniProt
- Q9NPI1
抗原
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