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BVES 抗体 (AA 241-360)

This anti-BVES antibody is a 兔 多克隆 antibody detecting BVES in ELISA 和 IF. Suitable for 人.
产品编号 ABIN7145640
发货至: 中国

Quick Overview for BVES 抗体 (AA 241-360) (ABIN7145640)

抗原

See all BVES 抗体
BVES (Blood Vessel Epicardial Substance (BVES))

适用

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宿主

  • 23
  • 3

克隆类型

  • 24
  • 2
多克隆

标记

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This BVES antibody is un-conjugated

应用范围

  • 19
  • 13
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  • 1
ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 3
    • 2
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    • 1
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    • 1
    • 1
    AA 241-360

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Blood vessel epicardial substance protein (241-360AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    BVES (Blood Vessel Epicardial Substance (BVES))

    别名

    BVES

    背景

    Background: Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells (PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading (By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density (PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.

    Aliases: Blood vessel epicardial substance antibody, Bves antibody, hBVES antibody, MGC42413 antibody, POP 1 antibody, POP1 antibody, POPD1_HUMAN antibody, POPDC 1 antibody, POPDC1 antibody, Popeye domain containing 1 antibody, Popeye domain containing protein 1 antibody, Popeye domain-containing protein 1 antibody, Popeye protein 1 antibody

    UniProt

    Q8NE79
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