BATF 抗体 (AA 1-125)
Quick Overview for BATF 抗体 (AA 1-125) (ABIN7145275)
抗原
See all BATF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-125
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Basic leucine zipper transcriptional factor ATF-like protein (1-125AA)
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亚型
- IgG
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anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 34-125) antibody
BATF 适用: 人 ELISA, WB, IP 宿主: 小鼠 Monoclonal 8A12 unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 34-125) antibodyBATF 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 1-126) antibodyBATF 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7C8F3 unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) antibodyBATF 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 34-125) antibodyBATF 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 1-125) antibodyBATF 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (N-Term) antibodyBATF 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Basic Leucine Zipper ATF-like Transcription Factor (BATF) (AA 35-84) antibodyBATF 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 猴, Bat, Hamster WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BATF (Basic Leucine Zipper ATF-like Transcription Factor (BATF))
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别名
- BATF
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背景
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Background: AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system: specifically mediates the differentiation of T-helper 17 cells (Th17), follicular T-helper cells (TfH), CD8(+) dendritic cells and class-switch recombination (CSR) in B-cells. Acts via the formation of a heterodimer with JUNB that recognizes and binds DNA sequence 5\\\'-TGA[CG]TCA-3\\\'. The BATF-JUNB heterodimer also forms a complex with IRF4 (or IRF8) in immune cells, leading to recognition of AICE sequence (5\\\'-TGAnTCA/GAAA-3\\\'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 (or IRF8) and activation of genes. Controls differentiation of T-helper cells producing interleukin-17 (Th17 cells) by binding to Th17-associated gene promoters: regulates expression of the transcription factor RORC itself and RORC target genes such as IL17 (IL17A or IL17B). Also involved in differentiation of follicular T-helper cells (TfH) by directing expression of BCL6 and MAF. In B-cells, involved in class-switch recombination (CSR) by controlling the expression of both AICDA and of germline transcripts of the intervening heavy-chain region and constant heavy-chain region (I(H)-C(H)). Following infection, can participate in CD8(+) dendritic cell differentiation via interaction with IRF4 and IRF8 to mediate cooperative gene activation. Regulates effector CD8(+) T-cell differentiation by regulating expression of SIRT1. Following DNA damage, part of a differentiation checkpoint that limits self-renewal of hematopoietic stem cells (HSCs): up-regulated by STAT3, leading to differentiation of HSCs, thereby restricting self-renewal of HSCs (By similarity).
Aliases: Activating transcription factor B antibody, B ATF antibody, B-ATF antibody, B-cell-activating transcription factor antibody, Basic leucine zipper transcription factor like antibody, Basic leucine zipper transcriptional factor ATF like antibody, Basic leucine zipper transcriptional factor ATF-like antibody, Batf antibody, BATF_HUMAN antibody, BATF1 antibody, SF HT activated gene 2 protein antibody, SF-HT-activated gene 2 protein antibody, SFA 2 antibody, SFA-2 antibody, SFA2 antibody
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UniProt
- Q16520
抗原
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