BAG3 抗体 (AA 220-420) (Biotin)
Quick Overview for BAG3 抗体 (AA 220-420) (Biotin) (ABIN7145215)
抗原
See all BAG3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 220-420
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交叉反应
- 人
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纯化方法
- >95%, Antigen Affinity purified & Affinity purified
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免疫原
- Recombinant Human BAG family molecular chaperone regulator 3 protein (220-420AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BAG3 (BCL2-Associated Athanogene 3 (BAG3))
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别名
- BAG3
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背景
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Background: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:9873016, PubMed:27474739). Has anti-apoptotic activity (PubMed:10597216). Plays a role in the HSF1 nucleocytoplasmic transport (PubMed:26159920).
Aliases: BAG 3 antibody, BAG family molecular chaperone regulator 3 antibody, BAG-3 antibody, Bag3 antibody, BAG3_HUMAN antibody, Bcl 2 binding protein antibody, Bcl-2-associated athanogene 3 antibody, Bcl-2-binding protein Bis antibody, BCL2 associated athanogene 3 antibody, BCL2 binding athanogene 3 antibody, BIS antibody, CAIR 1 antibody, Docking protein CAIR 1 antibody, Docking protein CAIR-1 antibody, MFM6 antibody
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UniProt
- O95817
抗原
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