CD22 抗体 (AA 708-847)
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- 抗原 See all CD22 抗体
- CD22 (CD22 Molecule (CD22))
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抗原表位
- AA 708-847
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CD22 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- Antigen Affinity Purified
- 免疫原
- Recombinant Human B-cell receptor CD22 protein (708-847AA)
- 亚型
- IgG
- Top Product
- Discover our top product CD22 Primary Antibody
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- 应用备注
- Recommended dilution: IHC:1:20-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- CD22 (CD22 Molecule (CD22))
- 别名
- CD22 (CD22 产品)
- 背景
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Background: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Aliases: B cell receptor CD22 precursor antibody, B lymphocyte cell adhesion molecule antibody, B-cell receptor CD22 antibody, B-lymphocyte cell adhesion molecule antibody, BL CAM antibody, BL-CAM antibody, BLCAM antibody, CD 22 antibody, CD22 antibody, CD22 antigen antibody, CD22 Molecule antibody, CD22 protein antibody, CD22_HUMAN antibody, Lectin 2 antibody, Leu14 antibody, Lyb8 antibody, MGC130020 antibody, sialic acid binding Ig like lectin 2 antibody, Sialic acid binding immunoglobulin like lectin 2 antibody, Sialic acid-binding Ig-like lectin 2 antibody, SIGLEC 2 antibody, Siglec-2 antibody, SIGLEC2 antibody, T cell surface antigen Leu 14 antibody, T-cell surface antigen Leu-14 antibody
- UniProt
- P20273
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