B-Cell Linker 抗体 (AA 41-337)
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北京 101111
Quick Overview for B-Cell Linker 抗体 (AA 41-337) (ABIN7145158)
抗原
See all B-Cell Linker (BLNK) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 41-337
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原理
- BLNK Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human B-cell linker protein (41-337AA)
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亚型
- IgG
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anti-B-Cell Linker (BLNK) antibody
BLNK 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5G9 unconjugated
anti-B-Cell Linker (BLNK) (AA 65-314) antibodyBLNK 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (C-Term) antibodyVerified BLNK 适用: 人 WB, ELISA, FACS, IF 宿主: 山羊 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (AA 301-400) antibodyBLNK 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-B-Cell Linker (BLNK) (pTyr96) antibodyBLNK 适用: 人 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr96) antibodyBLNK 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (N-Term) antibodyBLNK 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) (pTyr84) antibodyBLNK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) antibodyBLNK 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell Linker (BLNK) antibodyBLNK 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- B-Cell Linker (BLNK)
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别名
- BLNK
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背景
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Background: Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.
Aliases: AGM4 antibody, B cell adapter containing SH2 domain protein antibody, B cell adapter containing Src homology 2 domain protein antibody, B cell adaptor containing SH2 domain antibody, B cell linker antibody, B cell linker protein antibody, B cell-specific adaptor protein antibody, B-cell activation antibody, B-cell adapter containing a SH2 domain protein antibody, B-cell adapter containing a Src homology 2 domain protein antibody, B-cell linker protein antibody, BASH antibody, Bca antibody, BLNK antibody, BLNK s antibody, BLNK_HUMAN antibody, Cytoplasmic adapter protein antibody, Ly 57 antibody, Ly57 antibody, Lymphocyte antigen 57 antibody, Lyw 57 antibody, Lyw57 antibody, MGC111051 antibody, SH2 domain-containing leukocyte protein, 65-KD antibody, SLP 65 antibody, SLP-65 antibody, SLP65 antibody, Src homology [SH2] domain-containing leukocyte protein of 65 kD antibody, Src homology 2 domain containing leukocyte protein of 65 kDa antibody, Src homology 2 domain-containing leukocyte protein of 65 kDa antibody
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UniProt
- Q8WV28
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途径
- BCR Signaling
抗原
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