DHX36 抗体 (AA 68-181)
Quick Overview for DHX36 抗体 (AA 68-181) (ABIN7145003)
抗原
See all DHX36 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 68-181
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human ATP-dependent RNA helicase DHX36 protein (68-181AA)
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亚型
- IgG
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anti-DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36) (AA 1-260) antibody
DHX36 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))
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别名
- DHX36
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背景
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Background: Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component (TERC) 5\'-end (nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5\'-end to promote P1 helix formation, the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3\'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification.
Aliases: DDX36 antibody, DEAH box protein 36 antibody, Dhx36 antibody, DHX36_HUMAN antibody, EC 3.6.1.- antibody, KIAA1488 antibody, MLE like protein 1 antibody, MLE-like protein 1 antibody, MLEL1 antibody, Probable ATP dependent RNA helicase DHX36 antibody, Probable ATP-dependent RNA helicase DHX36 antibody, RHAU antibody, RNA helicase associated with AU rich element ARE antibody, RNA helicase associated with AU-rich element ARE antibody
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UniProt
- Q9H2U1
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途径
- Toll-Like Receptors Cascades
抗原
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