DDX42 抗体 (AA 519-819)
Quick Overview for DDX42 抗体 (AA 519-819) (ABIN7144990)
抗原
See all DDX42 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 519-819
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human ATP-dependent RNA helicase DDX42 protein (519-819AA)
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亚型
- IgG
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anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42) (AA 1-819) antibody
DDX42 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42) (C-Term) antibodyDDX42 适用: 人, 小鼠 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42) (AA 104-138) antibodyDDX42 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB54203 unconjugated
anti-DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42) antibodyDDX42 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:500,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))
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别名
- DDX42
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背景
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Background: ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modulate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimulating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm.
Aliases: DDX42ATP-dependent RNA helicase DDX42 antibody, EC 3.6.4.13 antibody, DEAD box protein 42 antibody, RNA helicase-like protein antibody, RHELP antibody, RNA helicase-related protein antibody, RNAHP antibody, SF3b DEAD box protein antibody, Splicing factor 3B-associated 125 kDa protein antibody, SF3b125 antibody
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UniProt
- Q86XP3
抗原
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