PIF1 抗体 (AA 125-360) (HRP)
Quick Overview for PIF1 抗体 (AA 125-360) (HRP) (ABIN7144967)
抗原
See all PIF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 125-360
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human ATP-dependent DNA helicase PIF1 protein (125-360AA)
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亚型
- IgG
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anti-PIF1 5'-To-3' DNA Helicase (PIF1) (AA 125-360) antibody
PIF1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PIF1 5'-To-3' DNA Helicase (PIF1) (Internal Region) antibodyPIF1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-PIF1 5'-To-3' DNA Helicase (PIF1) antibodyPIF1 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))
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别名
- PIF1
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背景
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Background: DNA-dependent ATPase and 5\\\'-3\\\' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
Aliases: ATP dependent DNA helicase PIF1 antibody, ATP-dependent DNA helicase PIF1 antibody, C15orf20 antibody, DNA helicase homolog PIF1 antibody, DNA helicase PIF1 antibody, DNA repair and recombination helicase PIF1 antibody, Petite integration frequency 1 antibody, PIF antibody, PIF1 5' to 3' DNA helicase antibody, PIF1 5' to 3' DNA helicase homolog antibody, PIF1 antibody, PIF1 DNA helicase antibody, PIF1/RRM3 DNA helicase like protein antibody, PIF1/RRM3 DNA helicase-like protein antibody, PIF1_HUMAN antibody
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UniProt
- Q9H611
抗原
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