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Asporin 抗体 (AA 33-380) (HRP)

This HRP-conjugated 兔 多克隆 anti-Asporin antibody specifically detects Asporin in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7144764
发货至: 中国
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Quick Overview for Asporin 抗体 (AA 33-380) (HRP) (ABIN7144764)

抗原

See all Asporin (ASPN) 抗体
Asporin (ASPN)

适用

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宿主

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克隆类型

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多克隆

标记

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This Asporin antibody is conjugated to HRP

应用范围

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ELISA
  • 抗原表位

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    AA 33-380

    原理

    ASPN Antibody, HRP conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Asporin protein (33-380AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    Asporin (ASPN)

    别名

    ASPN

    背景

    Background: Negatively regulates periodontal ligament (PDL) differentiation and mineralization to ensure that the PDL is not ossified and to maintain homeostasis of the tooth-supporting system. Inhibits BMP2-induced cytodifferentiation of PDL cells by preventing its binding to BMPR1B/BMP type-1B receptor, resulting in inhibition of BMP-dependent activation of SMAD proteins (By similarity). Critical regulator of TGF-beta in articular cartilage and plays an essential role in cartilage homeostasis and osteoarthritis (OA) pathogenesis. Negatively regulates chondrogenesis in the articular cartilage by blocking the TGF-beta/receptor interaction on the cell surface and inhibiting the canonical TGF-beta/Smad signal. Binds calcium and plays a role in osteoblast-driven collagen biomineralization activity.

    Aliases: ASPN antibody, ASPN protein antibody, ASPN_HUMAN antibody, Asporin (LRR class 1) antibody, Asporin antibody, Asporin proteoglycan antibody, FLJ20129 antibody, LRR class 1 antibody, Periodontal ligament associated protein 1 antibody, Periodontal ligament-associated protein 1 antibody, PLAP 1 antibody, PLAP-1 antibody, PLAP1 antibody, SLRR 1C antibody, SLRR1C antibody, Small leucine rich protein 1C antibody

    UniProt

    Q9BXN1
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