AHRR 抗体 (AA 255-506) (HRP)
Quick Overview for AHRR 抗体 (AA 255-506) (HRP) (ABIN7144664)
抗原
See all AHRR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 255-506
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Aryl hydrocarbon receptor repressor protein (255-506AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))
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别名
- AHRR
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背景
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Background: Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.
Aliases: AHH antibody, AhR repressor antibody, AhRR antibody, AHRR_HUMAN antibody, aryl hydrocarbon hydroxylase regulator antibody, aryl hydrocarbon receptor regulator antibody, Aryl hydrocarbon receptor repressor antibody, Arylhydrocarbon receptor repressor antibody, bHLHe77 antibody, Class E basic helix-loop-helix protein 77 antibody, Dioxin receptor repressor antibody, KIAA1234 antibody, MGC167813 antibody, MGC176630 antibody, OTTHUMP00000221488 antibody, OTTHUMP00000221489 antibody
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UniProt
- A9YTQ3
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途径
- Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha
抗原
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