ARPIN 抗体 (AA 1-226)
Quick Overview for ARPIN 抗体 (AA 1-226) (ABIN7144631)
抗原
See all ARPIN 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-226
-
交叉反应
- 人
-
纯化方法
- Antigen Affinity Purified
-
免疫原
- Recombinant Human Arpin protein (1-226AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- ARPIN
-
背景
-
Background: Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex, the function is competetive with nucleation promoting factors. Participates in an incoherent feedforward loop at the lamellipodium tip where it inhibits the ARP2/2 complex in response to Rac signaling and where Rac also stimulates actin polymerization through the WAVE complex. Involved in steering cell migration by controlling its directional persistence.
Aliases: 2610034B18Rik antibody, Actin related protein 2/3 complex inhibitor antibody, Arp2/3 inhibition protein antibody, ARPIN antibody, C15orf38 antibody, Chromosome 15 open reading frame 38 antibody, CO038_HUMAN antibody, Hypothetical protein LOC348110 antibody, MGC61550 antibody, RIKEN cDNA 2610034B18 antibody, UPF0552 protein C15orf38 antibody
-
UniProt
- Q7Z6K5
抗原
-