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ALOX15 抗体 (AA 1-225) (Biotin)

This Biotin-conjugated 兔 多克隆 anti-ALOX15 antibody specifically detects ALOX15 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7144539
发货至: 中国
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Quick Overview for ALOX15 抗体 (AA 1-225) (Biotin) (ABIN7144539)

抗原

See all ALOX15 抗体
ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

适用

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宿主

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克隆类型

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多克隆

标记

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This ALOX15 antibody is conjugated to Biotin

应用范围

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ELISA
  • 抗原表位

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    AA 1-225

    原理

    ALOX15 Antibody, Biotin conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Arachidonate 15-lipoxygenase protein (1-225AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))

    别名

    ALOX15

    背景

    Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.

    Aliases: 15 lipoxygenase 1 antibody, 15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE antibody, 15 LOX antibody, 15 LOX 1 antibody, 15-LOX antibody, 15LOX 1 antibody, ALOX15 antibody, Arachidonate 15 lipoxygenase antibody, Arachidonate 15-lipoxygenase antibody, Arachidonate omega 6 lipoxygenase antibody, Arachidonate omega-6 lipoxygenase antibody, LOG15 antibody, LOX15_HUMAN antibody

    UniProt

    P16050

    途径

    Regulation of Actin Filament Polymerization
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