ALOX15 抗体 (AA 1-225)
Quick Overview for ALOX15 抗体 (AA 1-225) (ABIN7144538)
抗原
See all ALOX15 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-225
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Arachidonate 15-lipoxygenase protein (1-225AA)
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亚型
- IgG
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anti-Arachidonate 15-Lipoxygenase (ALOX15) antibody
ALOX15 适用: 人, 大鼠, 猴, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 3G8 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-662) antibodyALOX15 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D8 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 2-337) antibodyALOX15 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 170-312) antibodyALOX15 适用: 人 WB 宿主: 小鼠 Monoclonal 6# unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (Internal Region) antibodyVerified ALOX15 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-662) antibodyALOX15 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 610-643), (C-Term) antibodyALOX15 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17156 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 1-663) antibodyALOX15 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3D8 unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) antibodyALOX15 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arachidonate 15-Lipoxygenase (ALOX15) (AA 170-312) antibodyALOX15 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ALOX15 (Arachidonate 15-Lipoxygenase (ALOX15))
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别名
- ALOX15
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背景
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Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3. Probably plays an important role in the immune and inflammatory responses. Through the oxygenation of membrane-bound phosphatidylethanolamine in macrophages may favor clearance of apoptotic cells during inflammation by resident macrophages and prevent an autoimmune response associated with the clearance of apoptotic cells by inflammatory monocytes. In parallel, may regulate actin polymerization which is crucial for several biological processes, including macrophage function. May also regulate macrophage function through regulation of the peroxisome proliferator activated receptor signaling pathway. Finally, it is also involved in the cellular response to IL13/interleukin-13. In addition to its role in the immune and inflammatory responses, may play a role in epithelial wound healing in the cornea maybe through production of lipoxin A4. May also play a role in endoplasmic reticulum stress response and the regulation of bone mass.
Aliases: 15 lipoxygenase 1 antibody, 15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE antibody, 15 LOX antibody, 15 LOX 1 antibody, 15-LOX antibody, 15LOX 1 antibody, ALOX15 antibody, Arachidonate 15 lipoxygenase antibody, Arachidonate 15-lipoxygenase antibody, Arachidonate omega 6 lipoxygenase antibody, Arachidonate omega-6 lipoxygenase antibody, LOG15 antibody, LOX15_HUMAN antibody
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UniProt
- P16050
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途径
- Regulation of Actin Filament Polymerization
抗原
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