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ALOX12 抗体 (AA 508-658) (HRP)

This HRP-conjugated 兔 多克隆 anti-ALOX12 antibody specifically detects ALOX12 in ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7144531
发货至: 中国
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Quick Overview for ALOX12 抗体 (AA 508-658) (HRP) (ABIN7144531)

抗原

See all ALOX12 抗体
ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

适用

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宿主

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克隆类型

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多克隆

标记

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This ALOX12 antibody is conjugated to HRP

应用范围

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ELISA
  • 抗原表位

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    AA 508-658

    原理

    ALOX12 Antibody, HRP conjugated

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Arachidonate 12-lipoxygenase, 12S-type protein (508-658AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ALOX12 (Arachidonate 12-Lipoxygenase (ALOX12))

    别名

    ALOX12

    背景

    Background: Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Mainly converts arachidonic acid to (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE but can also metabolize linoleic acid. Has a dual activity since it also converts leukotriene A4/LTA4 into both the bioactive lipoxin A4/LXA4 and lipoxin B4/LXB4. Through the production of specific bioactive lipids like (12S)-HPETE it regulates different biological processes including platelet activation. It also probably positively regulates angiogenesis through regulation of the expression of the vascular endothelial growth factor. Plays a role in apoptotic process, promoting the survival of vascular smooth muscle cells for instance. May also play a role in the control of cell migration and proliferation.

    Aliases: 12 LOX antibody, 12(S) lipoxygenase antibody, 12-lipoxygenase antibody, 12LO antibody, 12S LOX antibody, 12S-lipoxygenase antibody, 12S-LOX antibody, 12S-type antibody, Alox12 antibody, Arachidonate 12 lipoxygenase antibody, Arachidonate 12 lipoxygenase, 12S type antibody, Arachidonate 12-lipoxygenase antibody, Arachidonate 12-oxidoreductase antibody, Lipoxin synthase 12-LO antibody, LOG12 antibody, LOX12_HUMAN antibody, P-12LO antibody, Platelet 12-LOX antibody, Platelet type lipoxygenase 12 antibody, platelet-type 12-lipoxygenase antibody, Platelet-type lipoxygenase 12 antibody

    UniProt

    P18054

    途径

    Positive Regulation of Endopeptidase Activity
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