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ANAPC2 抗体 (AA 1-230)

This anti-ANAPC2 antibody is a 兔 多克隆 antibody detecting ANAPC2 in ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN7144072
发货至: 中国

Quick Overview for ANAPC2 抗体 (AA 1-230) (ABIN7144072)

抗原

See all ANAPC2 抗体
ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

适用

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宿主

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克隆类型

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多克隆

标记

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This ANAPC2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 1-230

    交叉反应

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Anaphase-promoting complex subunit 2 protein (1-230AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: IHC:1:20-1:500, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ANAPC2 (Anaphase Promoting Complex Subunit 2 (ANAPC2))

    别名

    ANAPC2

    背景

    Background: Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of \\\'Lys-11\\\'-linked polyubiquitin chains and, to a lower extent, the formation of \\\'Lys-48\\\'- and \\\'Lys-63\\\'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.

    Aliases: anapc2 antibody, Anaphase promoting complex subunit 2 antibody, Anaphase-promoting complex subunit 2 antibody, ANC2_HUMAN antibody, APC2 antibody, Cyclosome subunit 2 antibody, KIAA1406 antibody, OTTHUMP00000022692 antibody, RP11 350O14.5 antibody

    UniProt

    Q9UJX6

    途径

    Regulation of Cell Size
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