CD13 抗体 (AA 34-219)
Quick Overview for CD13 抗体 (AA 34-219) (ABIN7144005)
抗原
See all CD13 (ANPEP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 34-219
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交叉反应
- 人, 小鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Aminopeptidase N protein (34-219AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CD13 (ANPEP) (Alanyl (Membrane) Aminopeptidase (ANPEP))
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别名
- ANPEP
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背景
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Background: Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types, responsible for the processing of peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection.
Aliases: Alanyl (membrane) aminopeptidase antibody, Alanyl aminopeptidase antibody, Aminopeptidase M antibody, Aminopeptidase N antibody, AMPN_HUMAN antibody, ANPEP antibody, AP M antibody, AP N antibody, AP-M antibody, AP-N antibody, APN antibody, CD 13 antibody, CD13 antibody, CD13 antigen antibody, gp150 antibody, hAPN antibody, LAP 1 antibody, LAP1 antibody, Microsomal aminopeptidase antibody, Myeloid plasma membrane glycoprotein CD13 antibody, p150 antibody, PEPN antibody
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UniProt
- P15144
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途径
- Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones
抗原
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