A2ML1 抗体 (AA 625-751)
Quick Overview for A2ML1 抗体 (AA 625-751) (ABIN7143798)
抗原
See all A2ML1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 625-751
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Alpha-2-macroglobulin-like protein 1 protein (625-751AA)
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亚型
- IgG
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anti-alpha-2-Macroglobulin-Like 1 (A2ML1) (AA 1119-1348) antibody
A2ML1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-alpha-2-Macroglobulin-Like 1 (A2ML1) (AA 1-158) antibodyA2ML1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-alpha-2-Macroglobulin-Like 1 (A2ML1) (AA 1-158) antibodyA2ML1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-alpha-2-Macroglobulin-Like 1 (A2ML1) (AA 345-373), (N-Term) antibodyA2ML1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB24981 unconjugated
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- A2ML1 (alpha-2-Macroglobulin-Like 1 (A2ML1))
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别名
- A2ML1
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背景
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Background: Is able to inhibit all four classes of proteinases by a unique \\\'trapping\\\' mechanism. This protein has a peptide stretch, called the \\\'bait region\\\' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase (By similarity). Displays inhibitory activity against chymotrypsin, papain, thermolysin, subtilisin A and, to a lesser extent, elastase but not trypsin. May play an important role during desquamation by inhibiting extracellular proteases.
Aliases: A2ML1 antibody, CPAMD9Alpha-2-macroglobulin-like protein 1 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9 antibody
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UniProt
- A8K2U0
抗原
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