ALKBH8 抗体 (AA 1-230)
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北京 101111
Quick Overview for ALKBH8 抗体 (AA 1-230) (ABIN7143718)
抗原
See all ALKBH8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-230
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原理
- ALKBH8 Antibody
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纯化方法
- Antigen Affinity Purified
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免疫原
- Recombinant Human Alkylated DNA repair protein alkB homolog 8 protein (1-230AA)
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亚型
- IgG
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anti-AlkB, Alkylation Repair Homolog 8 (ALKBH8) (AA 1-230) antibody
ALKBH8 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 8 (ALKBH8) antibodyALKBH8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 8 (ALKBH8) (AA 494-523), (C-Term) antibodyALKBH8 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB19549 unconjugated
anti-AlkB, Alkylation Repair Homolog 8 (ALKBH8) (AA 141-190) antibodyALKBH8 适用: 人, 小鼠, 豚鼠, 马, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 8 (ALKBH8) (N-Term) antibodyALKBH8 适用: 人, 豚鼠, 马, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ALKBH8 (AlkB, Alkylation Repair Homolog 8 (ALKBH8))
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别名
- ALKBH8
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背景
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Background: Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its methyltransferase domain (PubMed:20123966, PubMed:20308323). Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA (PubMed:20123966, PubMed:20308323). Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys)(PubMed:20308323). Binds tRNA and catalyzes the iron and alpha-ketoglutarate dependent hydroxylation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA via its dioxygenase domain, giving rise to 5-(S)-methoxycarbonylhydroxymethyluridine, has a preference for tRNA(Gly) (PubMed:21285950). Required for normal survival after DNA damage (PubMed:20308323). May inhibit apoptosis and promote cell survival and angiogenesis (PubMed:19293182).
Aliases: 4930562C03Rik antibody, 8030431D03Rik antibody, 9430088N01Rik antibody, ABH8 antibody, alkB alkylation repair homolog 8 (E. coli) antibody, alkB alkylation repair homolog 8 antibody, AlkB homologue 8 antibody, ALKB8_HUMAN antibody, ALKBH8 antibody, Alkylated DNA repair protein alkB homolog 8 antibody, FLJ38204 antibody, MGC10235 antibody, OTTHUMP00000211286 antibody, OTTHUMP00000211287 antibody, Probable alpha-ketoglutarate-dependent dioxygenase ABH8 antibody, RGD1304687 antibody, S-adenosyl-L-methionine-dependent tRNA methyltransferase ABH8 antibody, tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ABH8 antibody
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UniProt
- Q96BT7
抗原
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