AGRP 抗体 (AA 83-132)
Quick Overview for AGRP 抗体 (AA 83-132) (ABIN7143593)
抗原
See all AGRP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 83-132
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Agouti-related protein (83-132AA)
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亚型
- IgG
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- AGRP (Agouti Related Protein Homolog (Mouse) (AGRP))
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别名
- AGRP
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背景
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Background: Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.
Aliases: Agouti related neuropeptide antibody, Agouti Related Protein Homolog antibody, Agouti-related protein antibody, Agrp antibody, AGRP_HUMAN antibody, AGRT antibody, ART antibody, ASIP2 antibody
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UniProt
- O00253
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途径
- Feeding Behaviour, Photoperiodism
抗原
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