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SSX2IP 抗体 (AA 485-614)

This anti-SSX2IP antibody is a 兔 多克隆 antibody detecting SSX2IP in ELISA, WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN7143574
发货至: 中国

Quick Overview for SSX2IP 抗体 (AA 485-614) (ABIN7143574)

抗原

See all SSX2IP 抗体
SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))

适用

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宿主

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克隆类型

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多克隆

标记

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This SSX2IP antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 485-614

    交叉反应

    人, 大鼠

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Afadin- and alpha-actinin-binding protein (485-614AA)

    亚型

    IgG
  • 应用备注

    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))

    别名

    SSX2IP

    背景

    Background: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73, the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (PubMed:23816619, PubMed:26545777). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449).

    Aliases: ADIP antibody, ADIP_HUMAN antibody, Afadin and alpha actinin binding protein antibody, Afadin DIL domain interacting protein antibody, Afadin DIL domain-interacting protein antibody, Afadin- and alpha-actinin-binding protein antibody, FLJ10848 antibody, KIAA0923 antibody, MGC75026 antibody, OTTHUMP00000011574 antibody, SSX 2 interacting protein antibody, SSX2 interacting protein antibody, SSX2-interacting protein antibody, SSX2IP antibody, Synovial sarcoma X breakpoint 2 interacting protein antibody

    UniProt

    Q9Y2D8
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