SSX2IP 抗体 (AA 485-614)
Quick Overview for SSX2IP 抗体 (AA 485-614) (ABIN7143574)
抗原
See all SSX2IP 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 485-614
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                                            交叉反应
- 人, 大鼠
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                                            纯化方法
- >95%, Protein G purified
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                                            免疫原
- Recombinant Human Afadin- and alpha-actinin-binding protein (485-614AA)
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                                            亚型
- IgG
 
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                                            应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
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                        Preservative: 0.03 % Proclin 300
 Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
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                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C,-80 °C
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                                            储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - SSX2IP (Synovial Sarcoma, X Breakpoint 2 Interacting Protein (SSX2IP))
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                                            别名
- SSX2IP
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                                            背景
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                        Background: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadin and alpha-actinin (By similarity). Involved in cell movement: localizes at the leading edge of moving cells in response to PDGF and is required for the formation of the leading edge and the promotion of cell movement, possibly via activation of Rac signaling (By similarity). Acts as a centrosome maturation factor, probably by maintaining the integrity of the pericentriolar material and proper microtubule nucleation at mitotic spindle poles. The function seems to implicate at least in part WRAP73, the SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome (PubMed:23816619, PubMed:26545777). Involved in ciliogenesis (PubMed:24356449). It is required for targeted recruitment of the BBSome, CEP290, RAB8, and SSTR3 to the cilia (PubMed:24356449). Aliases: ADIP antibody, ADIP_HUMAN antibody, Afadin and alpha actinin binding protein antibody, Afadin DIL domain interacting protein antibody, Afadin DIL domain-interacting protein antibody, Afadin- and alpha-actinin-binding protein antibody, FLJ10848 antibody, KIAA0923 antibody, MGC75026 antibody, OTTHUMP00000011574 antibody, SSX 2 interacting protein antibody, SSX2 interacting protein antibody, SSX2-interacting protein antibody, SSX2IP antibody, Synovial sarcoma X breakpoint 2 interacting protein antibody 
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                                            UniProt
- Q9Y2D8
 抗原
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