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ACD 抗体 (AA 328-497) (HRP)

This anti-ACD antibody is a 兔 多克隆 antibody detecting ACD in ELISA. Suitable for 人.
产品编号 ABIN7143549
发货至: 中国

Quick Overview for ACD 抗体 (AA 328-497) (HRP) (ABIN7143549)

抗原

See all ACD 抗体
ACD (Adrenocortical Dysplasia Homolog (ACD))

适用

  • 31
  • 14
  • 8
  • 3
  • 3
  • 3
  • 3
  • 1

宿主

  • 29
  • 7
  • 1

克隆类型

  • 32
  • 5
多克隆

标记

  • 27
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
This ACD antibody is conjugated to HRP

应用范围

  • 27
  • 10
  • 7
  • 7
  • 5
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
ELISA
  • 抗原表位

    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 328-497

    交叉反应

    纯化方法

    >95%, Protein G purified

    免疫原

    Recombinant Human Adrenocortical dysplasia protein homolog protein (328-497AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    ACD (Adrenocortical Dysplasia Homolog (ACD))

    别名

    ACD

    背景

    Background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends. Without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by recruiting telomerase to telomeres and increasing its processivity. May play a role in organogenesis.

    Aliases: Acd antibody, ACD_HUMAN antibody, Adrenocortical dysplasia homolog antibody, Adrenocortical dysplasia protein homolog antibody, PIP1 antibody, POT1 and TIN2 organizing protein antibody, POT1 and TIN2-interacting protein antibody, TIN2 interacting protein 1 antibody, TINT1 antibody, TPP1 antibody

    UniProt

    Q96AP0

    途径

    Telomere Maintenance
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