Adhesion G Protein-Coupled Receptor G1 (ADGRG1) (AA 26-216) 抗体
Quick Overview for Adhesion G Protein-Coupled Receptor G1 (ADGRG1) (AA 26-216) 抗体 (ABIN7143399)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-216
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human Adhesion G-protein coupled receptor G1 protein (26-216AA)
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亚型
- IgG
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anti-Adhesion G Protein-Coupled Receptor G1 (ADGRG1) (AA 86-109), (Extracellular) antibody
ADGRG1 适用: 大鼠 FACS, WB, LCI 宿主: 兔 Polyclonal unconjugated
anti-Adhesion G Protein-Coupled Receptor G1 (ADGRG1) (Internal Region) antibodyADGRG1 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adhesion G Protein-Coupled Receptor G1 (ADGRG1) (AA 86-109), (Extracellular) antibody (FITC)ADGRG1 适用: 大鼠 FACS 宿主: 兔 Polyclonal FITC
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应用备注
- Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Adhesion G Protein-Coupled Receptor G1 (ADGRG1)
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别名
- ADGRG1
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背景
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Background: Receptor involved in cell adhesion and probably in cell-cell interactions. Mediates cell matrix adhesion in developing neurons and hematopoietic stem cells. Receptor for collagen III/COL3A1 in the developing brain and involved in regulation of cortical development, specifically in maintenance of the pial basement membrane integrity and in cortical lamination (By similarity). Binding to the COL3A1 ligand inhibits neuronal migration and activates the RhoA pathway by coupling to GNA13 and possibly GNA12 (PubMed:22238662). Plays a role in the maintenance of hematopoietic stem cells and/or leukemia stem cells in bone marrow niche (By similarity). Plays a critical role in cancer progression by inhibiting VEGFA production threreby inhibiting angiogenesis through a signaling pathway mediated by PRKCA (PubMed:16757564, PubMed:21724588). Plays an essential role in testis development (By similarity).
Aliases: 7 transmembrane protein with no EGF like N terminal domains 1 antibody, BFPP antibody, DKFZp781L1398 antibody, EGF TM7 like antibody, G protein coupled receptor 56 antibody, G-protein coupled receptor 56 antibody, GPR 56 antibody, Gpr56 antibody, GPR56_HUMAN antibody, Polymicrogyria bilateral frontoparietal antibody, Protein TM7XN1 antibody, TM7LN4 antibody, TM7XN1 antibody, TM7XN1 protein antibody
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UniProt
- Q9Y653
抗原
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