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MOCS3 抗体 (AA 279-404)

This anti-MOCS3 antibody is a 兔 多克隆 antibody detecting MOCS3 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN7143364
发货至: 中国
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Quick Overview for MOCS3 抗体 (AA 279-404) (ABIN7143364)

抗原

See all MOCS3 抗体
MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))

适用

  • 19
  • 12
  • 2

宿主

  • 21
  • 5

克隆类型

  • 24
  • 2
多克隆

标记

  • 18
  • 2
  • 2
  • 2
  • 1
  • 1
This MOCS3 antibody is un-conjugated

应用范围

  • 22
  • 13
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    AA 279-404

    原理

    MOCS3 Antibody

    交叉反应

    小鼠

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Adenylyltransferase and sulfurtransferase MOCS3 protein (279-404aa)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))

    别名

    MOCS3

    背景

    Background: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor, NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

    Aliases: Adenylyltransferase and sulfurtransferase MOCS3 (Molybdenum cofactor synthesis protein 3) (Molybdopterin synthase sulfurylase) (MPT synthase sulfurylase) [Includes: Molybdopterin-synthase adenylyltransferase (EC 2.7.7.80) (Adenylyltransferase MOCS3) (Sulfur carrier protein MOCS2A adenylyltransferase), Molybdopterin-synthase sulfurtransferase (EC 2.8.1.11) (Sulfur carrier protein MOCS2A sulfurtransferase) (Sulfurtransferase MOCS3)], MOCS3, UBA4

    UniProt

    O95396
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