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MOCS3 抗体 (AA 271-460)

This 兔 多克隆 antibody specifically detects MOCS3 in WB, ELISA 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7143362
发货至: 中国
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Quick Overview for MOCS3 抗体 (AA 271-460) (ABIN7143362)

抗原

See all MOCS3 抗体
MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))

适用

  • 19
  • 12
  • 2

宿主

  • 21
  • 5

克隆类型

  • 24
  • 2
多克隆

标记

  • 18
  • 2
  • 2
  • 2
  • 1
  • 1
This MOCS3 antibody is un-conjugated

应用范围

  • 22
  • 13
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 9
    • 6
    • 4
    • 2
    • 1
    AA 271-460

    原理

    MOCS3 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human Adenylyltransferase and sulfurtransferase MOCS3 protein (271-460AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    MOCS3 (Molybdenum Cofactor Synthesis 3 (MOCS3))

    别名

    MOCS3

    背景

    Background: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor, NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.

    Aliases: Adenylyltransferase MOCS3 antibody, dJ914P20.3 antibody, MGC9252 antibody, MOCS 3 antibody, MOCS3 antibody, MOCS3_HUMAN antibody, Molybdenum cofactor synthesis 3 antibody, Molybdenum cofactor synthesis protein 3 antibody, Molybdopterin synthase sulfurylase antibody, Molybdopterin-synthase sulfurtransferase antibody, MPT synthase sulfurylase antibody, Sulfur carrier protein MOCS2A adenylyltransferase antibody, Sulfur carrier protein MOCS2A sulfurtransferase antibody, Sulfurtransferase MOCS3 antibody, UBA 4 antibody, UBA4 ubiquitin activating enzyme E1 homolog antibody, UBA4 antibody

    UniProt

    O95396
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