Actin-Like 6B 抗体 (AA 1-280)
Quick Overview for Actin-Like 6B 抗体 (AA 1-280) (ABIN7143053)
抗原
See all Actin-Like 6B (ACTL6B) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-280
-
交叉反应
- 人
-
纯化方法
- Antigen Affinity Purified
-
免疫原
- Recombinant Human Actin-like protein 6B protein (1-280AA)
-
亚型
- IgG
-
-
anti-Actin-Like 6B (ACTL6B) (AA 1-280) antibody
ACTL6B 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) antibodyACTL6B 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) antibodyACTL6B 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) (AA 42-70), (N-Term) antibodyACTL6B 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26766 unconjugated
anti-Actin-Like 6B (ACTL6B) (Internal Region) antibodyACTL6B 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) (AA 42-70) antibodyACTL6B 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) (N-Term) antibodyACTL6B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Actin-Like 6B (ACTL6B) (AA 323-372) antibodyACTL6B 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- Actin-Like 6B (ACTL6B)
-
别名
- ACTL6B
-
背景
-
Background: Belongs to the chromatin remodeling brain-specific BAF (bBAF) complex, as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and is required for postmitotic neural development and dendritic outgrowth. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth. ACTL6B/BAF53B is not essential for assembly of the nBAF complex but is required for targeting the complex and CREST to the promoter of genes essential for dendritic growth .
Aliases: 53 kDa BRG1 associated factor B antibody, 53 kDa BRG1-associated factor B antibody, ACL 6B antibody, ACL6B antibody, ACL6B_HUMAN antibody, Actin like 6 antibody, Actin like protein 6B antibody, Actin like protein6B antibody, Actin related protein antibody, Actin related protein Baf53b antibody, actin-like 6B antibody, Actin-like protein 6B antibody, Actin-related protein Baf53b antibody, Actl 6 antibody, ACTL 6B antibody, Actl6 antibody, ACTL6 B antibody, Actl6b antibody, Arp Na antibody, ArpN a antibody, ArpN alpha antibody, ArpNa antibody, ArpNalpha antibody, Baf 53b antibody, BAF53B antibody, BRG1-associated factor 53B antibody
-
UniProt
- O94805
抗原
-
