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FAM107A 抗体 (AA 1-144)

This anti-FAM107A antibody is a 兔 多克隆 antibody detecting FAM107A in ELISA 和 IHC. Suitable for 人.
产品编号 ABIN7143032
发货至: 中国

Quick Overview for FAM107A 抗体 (AA 1-144) (ABIN7143032)

抗原

See all FAM107A 抗体
FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

适用

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宿主

  • 25
  • 4

克隆类型

  • 27
  • 2
多克隆

标记

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This FAM107A antibody is un-conjugated

应用范围

  • 11
  • 10
  • 7
  • 2
  • 1
ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 10
    • 2
    • 2
    • 1
    AA 1-144

    原理

    FAM107A Antibody

    纯化方法

    Protein G purified

    纯度

    >95 %

    免疫原

    Recombinant Human Actin-associated protein FAM107A protein (1-144AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

    别名

    FAM107A

    背景

    Background: Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin) dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity). Plays a role in the actin and microtubule cytoskeleton organization, negatively regulates focal adhesion (FA) assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner (PubMed:20543869). Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner (PubMed:10564580, PubMed:28604741). May play a role in tumor development (PubMed:10564580).

    Aliases: Down regulated in renal cell carcinoma 1 antibody, Down-regulated in renal cell carcinoma 1 antibody, Downregulated in renal cell carcinoma antibody, DRR1 antibody, F107A_HUMAN antibody, FAM107A antibody, Family with sequence similarity 107, member A antibody, FLJ30158 antibody, FLJ45473 antibody, Protein FAM107A antibody, Protein TU3A antibody, TU3A antibody

    UniProt

    O95990
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