ASIC1 抗体 (AA 195-297) (FITC)
-
- 抗原 See all ASIC1 (ACCN2) 抗体
- ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
-
抗原表位
- AA 195-297
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ASIC1 antibody is conjugated to FITC
- 应用范围
- 请咨询
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Acid-sensing ion channel 1 protein (195-297AA)
- 亚型
- IgG
- Top Product
- Discover our top product ACCN2 Primary Antibody
-
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (N-Term) antibody
ACCN2 适用: 小鼠, 人, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (C-Term) antibodyVerified ACCN2 适用: 小鼠, 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibodyACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 unconjugated
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (HRP)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 HRP
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (FITC)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 FITC
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (Alkaline Phosphatase (AP))ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 Alkaline Phosphatase (AP)
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (Biotin)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 Biotin
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (PE)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 PE
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (APC)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 APC
anti-Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2) (AA 460-526) antibody (PerCP)ACCN2 适用: 小鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal S271-44 PerCP
-
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 缓冲液
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- 抗原
- ASIC1 (ACCN2) (Amiloride-Sensitive Cation Channel 2, Neuronal (ACCN2))
- 别名
- ASIC1 (ACCN2 产品)
- 别名
- ACCN2 antibody, ASIC antibody, BNaC2 antibody, Accn2 antibody, ASIC1 antibody, AI843610 antibody, ASIC1a antibody, B530003N02Rik antibody, acid sensing ion channel subunit 1 antibody, acid-sensing (proton-gated) ion channel 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 antibody, ASIC1 antibody, Asic1 antibody, asic1 antibody, SMARCD1 antibody
- 背景
-
Background: Isoform 2 and isoform 3 function as proton-gated sodium channels, they are activated by a drop of the extracellular pH and then become rapidly desensitized. The channel generates a biphasic current with a fast inactivating and a slow sustained phase. Has high selectivity for sodium ions and can also transport lithium ions with high efficiency. Isoform 2 can also transport potassium, but with lower efficiency. It is nearly impermeable to the larger rubidium and cesium ions. Isoform 3 can also transport calcium ions. Mediates glutamate-independent Ca(2+) entry into neurons upon acidosis. This Ca(2+) overloading is toxic for cortical neurons and may be in part responsible for ischemic brain injury. Heteromeric channel assembly seems to modulate channel properties. Functions as a postsynaptic proton receptor that influences intracellular Ca(2+) concentration and calmodulin-dependent protein kinase II phosphorylation and thereby the density of dendritic spines. Modulates activity in the circuits underlying innate fear.
Aliases: ACCN2 antibody, ACCN2_HUMAN antibody, Acid sensing ion channel 1 antibody, Acid sensing ion channel 1a protein antibody, Acid sensing ion channel antibody, Acid-sensing ion channel 1 antibody, AI843610 antibody, Amiloride sensitive cation channel 2 neuronal antibody, Amiloride-sensitive cation channel 2 antibody, ASIC antibody, ASIC1 antibody, ASIC1A antibody, B530003N02Rik antibody, BNaC2 antibody, Brain sodium channel 2 antibody, Cation channel amiloride sensitive neuronal 2 antibody, hBNaC2 antibody, neuronal antibody
- UniProt
- P78348
-
