AKAP1 抗体 (AA 413-662)
Quick Overview for AKAP1 抗体 (AA 413-662) (ABIN7142902)
抗原
See all AKAP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 413-662
-
交叉反应
- 人
-
纯化方法
- Antigen Affinity Purified
-
免疫原
- Recombinant Human A-kinase anchor protein 10, mitochondrial protein (413-662AA)
-
亚型
- IgG
-
-
-
-
应用备注
- Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,-80 °C
-
储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))
-
别名
- AKAP1
-
背景
-
Background: Differentially targeted protein that binds to type I and II regulatory subunits of protein kinase A and anchors them to the mitochondria or the plasma membrane. Although the physiological relevance between PKA and AKAPS with mitochondria is not fully understood, one idea is that BAD, a proapoptotic member, is phosphorylated and inactivated by mitochondria-anchored PKA. It cannot be excluded too that it may facilitate PKA as well as G protein signal transduction, by acting as an adapter for assembling multiprotein complexes. With its RGS domain, it could lead to the interaction to G-alpha proteins, providing a link between the signaling machinery and the downstream kinase (By similarity).
Aliases: AKAP10A-kinase anchor protein 10 antibody, mitochondrial antibody, AKAP-10 antibody, Dual specificity A kinase-anchoring protein 2 antibody, D-AKAP-2 antibody, Protein kinase A-anchoring protein 10 antibody, PRKA10 antibody
-
UniProt
- O43572
-
途径
- Synaptic Membrane
抗原
-