RPL13A 抗体 (AA 63-190) (Biotin)
Quick Overview for RPL13A 抗体 (AA 63-190) (Biotin) (ABIN7142745)
抗原
See all RPL13A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 63-190
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human 60S ribosomal protein L13a protein (63-190AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RPL13A (Ribosomal Protein L13a (RPL13A))
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别名
- RPL13A
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背景
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Background: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3\'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA.
Aliases: RPL13A antibody, 60S ribosomal protein L13a antibody, 23 kDa highly basic protein antibody, Large ribosomal subunit protein uL13 antibody
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UniProt
- P40429
抗原
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