ERI1 抗体 (AA 2-66)
Quick Overview for ERI1 抗体 (AA 2-66) (ABIN7142343)
抗原
See all ERI1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-66
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交叉反应
- 人, 大鼠
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human 3\\\'-5\\\' exoribonuclease 1 protein (2-66AA)
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亚型
- IgG
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应用备注
- Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- ERI1 (Exoribonuclease 1 (ERI1))
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别名
- ERI1
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背景
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Background: RNA exonuclease that binds to the 3\\\'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2\\\' and 3\\\'-hydroxyl groups at the last nucleotide of the histone 3\\\'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3\\\'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5\\\'-ACCCA-3\\\' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3\\\'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs.
Aliases: 3' 5' exonuclease ERI 1 antibody, 3' 5' exonuclease ERI1 antibody, 3' EXO antibody, 3' exoribonuclease antibody, 3' HEXO antibody, 3' histone mRNA exonuclease 1 antibody, 3''-5'' exonuclease eri1 antibody, 3''-5'' exoribonuclease 1 antibody, 3'EXO antibody, 3'HEXO antibody, ERI 1 antibody, Eri 1 homolog antibody, Eri-1 homolog antibody, eri1 antibody, Eri1 homolog antibody, ERI1_HUMAN antibody, HEXO antibody, Histone mRNA 3' end specific exonuclease antibody, Histone mRNA 3' end specific exoribonuclease antibody, Histone mRNA 3''-end-specific exoribonuclease antibody, Histone mRNA 3''-exonuclease 1 antibody, MGC35395 antibody, Protein 3''hExo antibody, THEX 1 antibody, THEX1 antibody, Three prime histone mRNA exonuclease 1 antibody
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UniProt
- Q8IV48
抗原
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