PSMC6 抗体 (Regulatory Subunit)
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Quick Overview for PSMC6 抗体 (Regulatory Subunit) (ABIN7142226)
抗原
See all PSMC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-260, Regulatory Subunit
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原理
- PSMC6 Antibody
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交叉反应
- 小鼠, 大鼠
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Human 26S proteasome regulatory subunit 10B protein (1-260AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PSMC6 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 6 (PSMC6))
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别名
- PSMC6
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背景
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Background: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
Aliases: 26S protease regulatory subunit 10B antibody, 26S protease regulatory subunit S10B antibody, 26S proteasome AAA-ATPase subunit RPT4 antibody, CADP44 antibody, P44 antibody, Proteasome 26S subunit ATPase 6 antibody, Proteasome subunit p42 antibody, PRS10_HUMAN antibody, PSMC6 antibody, Rpt4 antibody, SUG2 antibody
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UniProt
- P62333
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
抗原
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