PLCD4 抗体 (AA 1-762)
Quick Overview for PLCD4 抗体 (AA 1-762) (ABIN7142054)
抗原
See all PLCD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-762
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交叉反应
- 人
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纯化方法
- >95%, Protein G purified
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免疫原
- Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 protein (1-762AA)
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亚型
- IgG
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anti-Phospholipase C, delta 4 (PLCD4) (AA 1-250) antibody
PLCD4 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C, delta 4 (PLCD4) (AA 18-127) antibodyPLCD4 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 4D4 unconjugated
anti-Phospholipase C, delta 4 (PLCD4) (AA 1-290) antibodyPLCD4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C, delta 4 (PLCD4) (AA 1-762) antibodyPLCD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Phospholipase C, delta 4 (PLCD4) (AA 1-290) antibodyPLCD4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Recommended dilution: IHC:1:20-1:200,
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- PLCD4 (Phospholipase C, delta 4 (PLCD4))
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别名
- PLCD4
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背景
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Background: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca2+ from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca2+ mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
Aliases: 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase delta 4 antibody, 1-phosphatidylinositol 4 antibody, 1-phosphatidylinositol-4 antibody, 5-bisphosphate phosphodiesterase delta-4 antibody, hPLCD4 antibody, MGC12837 antibody, Phosphoinositide phospholipase C delta 4 antibody, Phosphoinositide phospholipase C-delta-4 antibody, Phospholipase C delta 4 antibody, Phospholipase C-delta-4 antibody, PLC delta 4 antibody, PLC delta4 antibody, PLC-delta-4 antibody, PLCD4 antibody, PLCD4_HUMAN antibody
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UniProt
- Q9BRC7
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途径
- Inositol Metabolic Process
抗原
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