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PLCD4 抗体 (AA 1-290)

This 兔 多克隆 anti-PLCD4 antibody specifically detects PLCD4 in IHC, ELISA 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN7142053
发货至: 中国
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Quick Overview for PLCD4 抗体 (AA 1-290) (ABIN7142053)

抗原

See all PLCD4 抗体
PLCD4 (Phospholipase C, delta 4 (PLCD4))

适用

  • 13
  • 3
  • 3

宿主

  • 14
  • 3

克隆类型

  • 15
  • 2
多克隆

标记

  • 13
  • 2
  • 1
  • 1
This PLCD4 antibody is un-conjugated

应用范围

  • 11
  • 7
  • 7
  • 4
  • 2
  • 2
  • 1
Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

    • 7
    • 1
    • 1
    • 1
    • 1
    AA 1-290

    原理

    PLCD4 Antibody

    纯化方法

    Antigen Affinity Purified

    免疫原

    Recombinant Human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 protein (1-290AA)

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,-80 °C

    储存方法

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原

    PLCD4 (Phospholipase C, delta 4 (PLCD4))

    别名

    PLCD4

    背景

    Background: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.

    Aliases: 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase delta 4 antibody, 1-phosphatidylinositol 4 antibody, 1-phosphatidylinositol-4 antibody, 5-bisphosphate phosphodiesterase delta-4 antibody, hPLCD4 antibody, MGC12837 antibody, Phosphoinositide phospholipase C delta 4 antibody, Phosphoinositide phospholipase C-delta-4 antibody, Phospholipase C delta 4 antibody, Phospholipase C-delta-4 antibody, PLC delta 4 antibody, PLC delta4 antibody, PLC-delta-4 antibody, PLCD4 antibody, PLCD4_HUMAN antibody

    UniProt

    Q9BRC7

    途径

    Inositol Metabolic Process
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