Hepatitis E Virus ORF3 (HEV-1 ORF3) (AA 1-114) 抗体
Quick Overview for Hepatitis E Virus ORF3 (HEV-1 ORF3) (AA 1-114) 抗体 (ABIN7141954)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-114
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原理
- ORF3 Antibody
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Hepatitis E virus genotype 1 Protein ORF3 protein (1-114AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Hepatitis E Virus ORF3 (HEV-1 ORF3)
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别名
- Hepatitis E virus genotype 1 ORF3
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物质类
- Viral Protein
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背景
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Background: Plays critical roles in the final steps of viral release by interacting with host TSG101, a member of the vacuolar protein-sorting pathway and using other cellular host proteins involved in vesicle formation pathway. Acts also as a viroporin and forms ion conductive pores allowing viral particle release. Impairs the generation of type I interferon by downregulating host TLR3 and TLR7 as well as their downstream signaling pathways.
Aliases: ORF3 antibody, Protein ORF3 antibody, pORF3 antibody
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UniProt
- O90299
抗原
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