Hepatitis E Virus ORF1 (HEV-1 ORF1) (AA 60-240) 抗体 (Biotin)
Quick Overview for Hepatitis E Virus ORF1 (HEV-1 ORF1) (AA 60-240) 抗体 (Biotin) (ABIN7141951)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 60-240
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Virus Strain
- isolate Human/Pakistan/Sar-55
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原理
- ORF1 Antibody, Biotin conjugated
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交叉反应
- Hepatitis E Virus (HEV)
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纯化方法
- Protein G purified
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纯度
- >95 %
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免疫原
- Recombinant Hepatitis E virus genotype 1 Non-structural polyprotein pORF1 protein (60-240AA)
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Hepatitis E Virus ORF1 (HEV-1 ORF1)
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别名
- Hepatitis E virus genotype 1 (isolate Human/Pakistan/Sar-55) (HEV-1) ORF1
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物质类
- Viral Protein
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背景
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Background: Methyltransferase displays a cytoplasmic capping enzyme activity. This function is necessary since all viral RNAs are synthesized in the cytoplasm, and host capping enzymes are restricted to the nucleus. The enzymatic reaction involves a covalent link between 7-methyl-GMP and the methyltransferase, whereas eukaryotic capping enzymes form a covalent complex only with GMP. Methyltransferase catalyzes transfer of a methyl group from S-adenosylmethionine to GTP and GDP to yield m7GTP or m7GDP. GMP, GpppG, and GpppA were poor substrates for the methyltransferase. This enzyme also displays guanylyltransferase activity to form a covalent complex, methyltransferase-m7GMP, from which 7-methyl-GMP is transferred to the mRNA to create the cap structure. Cap analogs such as m7GTP, m7GDP, et2m7GMP, and m2et7GMP inhibit the methyltransferase reaction (By similarity).
Aliases: ORF1 antibody, Non-structural polyprotein pORF1 [Includes: Methyltransferase antibody, EC 2.1.1.- antibody, EC 2.7.7.-), Putative papain-like cysteine protease antibody, PLP antibody, EC 3.4.22.-), NTPase/helicase antibody, EC 3.6.4.-), RNA-directed RNA polymerase antibody, RdRp antibody, EC 2.7.7.48)] antibody
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UniProt
- P33424
抗原
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